Athymic Nude Rat Brain Atlas
  • Author : Bengt Mattsson
  • Release Date : 01 June 2023
  • Publisher : Elsevier
  • Genre : Medical
  • Pages : 0
  • ISBN 13 : 9780323997416
  • Total Download : 219
  • File Size : 53,8 Mb

Athymic Nude Rat Brain Atlas PDF Summary

Athymic Nude Rat Brain Atlas provides the first stereotaxic brain atlas of the athymic nude rat (Crl:NIH-Foxn1rnu), a T-cell deficient mouse model frequently used for experimental studies and pre-clinical safety and efficacy studies. This 2D vector-based atlas contains coronal, sagittal and horizontal brain sections of an athymic rat brain compared to SD rats both processed in parallel, stained with cresyl violet (Nissl) and placed in 3D using Cinema 4D using "flat" skull Bregma and Lambda as anatomical landmarks for correct placement in the 3D environment. Each brain structure is illustrated as a volume, making it easy to compare the two rat strains, allow for precise targeting, and better calculate coordinates to target specific structures for toxin, virus or cell delivery using stereotaxic surgery. This atlas will serve the needs of any neuroscientist who wishes to work with these mice in experimental and pre-clinical studies. In addition, it will serve as a valuable resource for the wider research community using nude rats. Features 2D vector-based color illustrations and 3D reconstructions Contains coronal, sagittal and horizontal views and Nissl stains Directly compares brain region, shape, size and relative location in SD rats and the athymic nude rat Allows for easy read-out of coordinates for precise injections using stereotactic surgery Includes 30 μm sections of each mouse strain placed in 3D using Cinema 4D and "flat" skull Bregma and Lambda as anatomical landmarks for correct placement in the 3D environment

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Author : Mark A. Suckow,F. Claire Hankenson,Ronald P. Wilson,Patricia L. Foley
Publisher : Academic Press
Total Download : 376
File Size : 43,8 Mb
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